Nonspherocytic

Nonspherocytic

Literally means not sphereshaped. Often in inherited hemolytic anemias, the red blood cells are sphere-shaped. In Nonspherocytic Hemolytic Anemias, the red blood cells are not sphere-shaped.
References in periodicals archive ?
The CD22 is a marker that is expressed in B cell development, and is expressed in mature B prior to their differentiation into plasma cells and identified in lung cancer, as well as lymphocytic leukemia, in chronic nonspherocytic hemolytic anemia, and systemic lupus erythematosus (Tuscano et al.
G6PD is an x-linked recessive disease where the deficiency of the enzyme causes a spectrum of clinical manifestations ranging from neonatal jaundice to chronic nonspherocytic anemia to infection and drug-induced hemolysis.
Glucose-6-phosphate dehydrogenase deficiency is an important disorder of hexos monophosphate pathway and is responsible for different clinical syndromes including neonatal jaundice, episodic hemolytic anemia induced by; infections, certain drugs and fava beans and spontaneous chronic nonspherocytic hemolytic anemia.
Deletion of leucine 61 in glucose-6-phosphate dehydrogenase leads to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections.
Clinical and haematological consequences of recurrent G6PD mutations and a single new mutation causing chronic nonspherocytic haemolytic anaemia.
Five unknown mutations in the LR pyruvate kinase gene associated with severe hereditary nonspherocytic haemolytic anemia in France.
Hereditary spherocytosis RBC spectrin RBC ankyrin Hereditary elliptocytosis RBC spectrin Hereditary pyropoikilocytosis RBC spectrin Hemolytic anemia - Glucose- G-6-PD 6-phosphate dehydrogenase deficiency Hereditary nonspherocytic PDH hemolytic anemia - Pyruvate kinase deficiency Porphyrias Various genes encoding enzymes of the heme biosynthesis pathway
Analysis of pyruvate kinase-deficiency mutations that produce nonspherocytic hemolytic anemia.