nimodipine


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nimodipine

 [ni-mo´dĭ-pēn]
a calcium channel blocking agent used as a vasodilator in the treatment of neurologic deficits associated with subarachnoid hemorrhage from a ruptured intracranial aneurysm; administered orally.

nimodipine

/ni·mo·di·pine/ (ni-mo´dĭ-pēn) a calcium channel blocker used as a vasodilator in the treatment of neurologic deficits associated with subarachnoid hemorrhage from a ruptured intracranial aneurysm.

nimodipine

(nə-mō′də-pēn′)
n.
A calcium channel blocker used to reduce neurological damage after subarachnoid hemorrhage.

nimodipine

[ni-mo′dĭpēn]
a calcium channel blocking agent used as a vasodilator in the treatment of neurological deficits associated with subarachnoid hemorrhage from a ruptured intracranial aneurysm, administered orally.

nimodipine

An dihydropyridine L-type calcium channel antagonist originally developed for treating hypertension; it is now used to prevent vasospasm in subarachnoid haemorrhage. Nimodipine preferentially binds to the channels when cells are depolarised, maintaining them in an opened state and theoretically preventing the accumulation of glutamate, which has been pathogenically linked to AIDS dementia complex.

nimodipine

A CALCIUM CHANNEL BLOCKER drug used to minimise brain damage after subarachnoid haemorrhage. A brand name is Nimotop.

Nimodipine (Nimotop)

A calcium-channel blocker, that is, a drug that relaxes arterial smooth muscle by slowing the movement of calcium across cell walls.
Mentioned in: Cerebral Aneurysm
References in periodicals archive ?
Received ANDA approval for Nimodipine capsules (via Sofgen partnership).
The therapeutic effects of melatonin and nimodipine in rats after cerebral cortical injury.
Oral nimodipine of 30-60 mg every 2 hours was administered in 24% of the observations; other oral antihypertensive medications were administered in 27%.
9), (10) When the calcium-channel blocker nimodipine was used by itself, learning was proved to take place faster in aged animals treated with the drug.
Effect of Nimodipine on Primphos-induced seizure in mice, Advances in Environmental Biology, 5(7): 1866-1870.
Design and evaluation of self-emulsifying drug delivery systems (SEDDS) of nimodipine.
Nimodipine in animal model experiments of focal cerebral ischemia: a systematic review.
nifedipine, nivadipine, nimodipine, nisolidipine, nitrerdipine,
It was combined in turn with four poorly water soluble drugs of different properties and biomedical functions: carvedilol (a nonselective adrenergic receptor blocker, indicated in the treatment of mild-to-moderate congestive heart failure), itraconazole (an antifungal agent that impairs ergosterol synthesis, used among others against histoplasmosis, cryptococcal meningitis, and aspergillosis), nevirapine (a potent, non-nucleoside reverse transcriptase inhibitor used for treatment of HIV infection and AIDS), and nimodipine (a calcium channel blockader with preferential cerebrovascular activity).
Methylprednisolone, nimodipine, magnesium, and tirilazad have thus far yielded negative results in humans and will not be further discussed in this review.