Nikolsky's sign


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Nikolsky's sign

 [nĭ-kol´skēz]
in pemphigus vulgaris and some other bullous diseases, the outer epidermis separates easily from the basal layer on exertion of firm sliding manual pressure.

Nikolsky's sign

[nikol′skēz]
Etymology: Petr V. Nikolsky, Russian dermatologist, 1858-1940
easy separation of the stratum corneum layer of the epidermis from the basal cell layer by rubbing apparently normal skin areas, found in pemphigus and a few other bullous diseases.

Nikolsky's sign

in pemphigus vulgaris and some other bullous diseases, the outer epidermis separates easily from the basal layer on exertion of firm sliding manual pressure.