Follow-up Patients were followed up regularly and monitored for any side effects of the therapy, clinical activity of the disease in terms of healing of existing lesions, appearance of new lesions and
Nikolsky's sign.
Bullae with a positive
Nikolsky's sign is present in TEN likewise, mucosal lesions accompany in all conscience.
Bulla spread sign and
nikolsky's sign were negative.
* Lesions can follow a minor trauma, called
Nikolsky's Sign, where cells pull apart and blister and lesions develop because the adhesion between cells is weakened.
A definitive diagnosis of PV is made when
Nikolsky's sign is positive, in the presence of acantholysis in histopathology and by direct immunofluorescence [2].