Nikolsky's sign


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.

Nikolsky's sign

 [nĭ-kol´skēz]
in pemphigus vulgaris and some other bullous diseases, the outer epidermis separates easily from the basal layer on exertion of firm sliding manual pressure.

Nikolsky's sign

[nikol′skēz]
Etymology: Petr V. Nikolsky, Russian dermatologist, 1858-1940
easy separation of the stratum corneum layer of the epidermis from the basal cell layer by rubbing apparently normal skin areas, found in pemphigus and a few other bullous diseases.

Nikolsky's sign

in pemphigus vulgaris and some other bullous diseases, the outer epidermis separates easily from the basal layer on exertion of firm sliding manual pressure.
References in periodicals archive ?
But dexamethasone group showed statistically more significant improvement than prednisolone group in all clinical parameters except Nikolsky's sign.
A positive Nikolsky's sign is characteristic of pemphigns vulgaris.