Nikolsky's sign


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Nikolsky's sign

 [nĭ-kol´skēz]
in pemphigus vulgaris and some other bullous diseases, the outer epidermis separates easily from the basal layer on exertion of firm sliding manual pressure.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Follow-up Patients were followed up regularly and monitored for any side effects of the therapy, clinical activity of the disease in terms of healing of existing lesions, appearance of new lesions and Nikolsky's sign.
Bullae with a positive Nikolsky's sign is present in TEN likewise, mucosal lesions accompany in all conscience.
Bulla spread sign and nikolsky's sign were negative.
A definitive diagnosis of PV is made when Nikolsky's sign is positive, in the presence of acantholysis in histopathology and by direct immunofluorescence [2].