nicotinic

(redirected from Nicotinic acetylcholine receptor)
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Related to Nicotinic acetylcholine receptor: Muscarinic acetylcholine receptor

nicotinic

 [nik″o-tin´ic]
pertaining to the transmission of nerve impulses mediated by nicotinic receptors.

nic·o·tin·ic

(nik'ō-tin'ik),
Relating to the stimulating action of acetylcholine and other nicotinelike agents on autonomic ganglia, adrenal medulla, and the motor end-plate of striated muscle.

nicotinic

/nic·o·tin·ic/ (nik″o-tin´ik) denoting the effect of nicotine and other drugs in initially stimulating and subsequently, in high doses, inhibiting neural impulses at autonomic ganglia and the neuromuscular junction.

nicotinic

(nĭk′ə-tĭn′ĭk, -tē′nĭk)
adj.
1. Of or relating to nicotine.
2. Of or relating to niacin.

nic·o·tin·ic

(nik'ō-tin'ik)
Relating to the stimulating action of acetylcholine and other nicotinelike agents on autonomic ganglia, medulla of suprarenal gland, and the motor end plate of striated muscle.

nicotinic

Having the effects of acetylcholine and other nicotine-like substances on autonomic ganglia and the neuromuscular junctions of voluntary muscle. Compare MUSCARINIC.

nicotinic

pertaining to the transmission of nerve impulses mediated by nicotinic receptors.

nicotinic acid
see niacin.
nicotinic receptors
cholinergic receptors of autonomic ganglion cells and motor end-plates of skeletal muscle that are stimulated by low doses of nicotine and blockaded by high doses or by tubocurarine.
nicotinic synapses
synapses in which nicotinic transmitters effect the transmission of impulses.

Patient discussion about nicotinic

Q. nicotine patch does anyone know if you can use the patch for smokeless tobacco users,that dont smoke,and how well does it work,what are the side effects,i"ve been using smokeless tobacco for 24 years and would like to stop,tried going cold turkey,but it didnt work,my dr. said i should try the patch,but couldnt tell me if it would work or not.

A. There is really no reason you couldn't try the patch. The problem would be with what dose to start. Usually if people smoke more than 10 cigarettes a day they start with the 21mg but I am not sure how smokeless tobacco relates to cigarettes. Your best bet may be to try the gum as you chew it and then place it between you cheek and gum for a while, similar to dip.

More discussions about nicotinic
References in periodicals archive ?
Bionomics' lead drug candidate BNC210, currently in Phase 2 for the treatment of generalized anxiety disorder, is a novel, proprietary negative allosteric modulator of the alpha-7 nicotinic acetylcholine receptor.
The IRAC mode of action groups to which the above insecticides belong are as follows: fipronil (2B, GABA-gated chloride channel antagonists), lambda-cyhalothrin (3A, Sodium channel modulators), imidacloprid, thiacloprid and thiamethoxam (4A, Nicotinic acetylcholine receptor [nAChR] agonists), and spinosad (5, Nicotinic acetylcholine receptor [nAChR] allosteric activators).
Varenicline, an a4ss2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation.
Selective changes in nicotinic acetylcholine receptor subtypes related to tobacco smoking: an immuno-histochemical study.
Varenicline is pharmacologically known as an alpha4beta2 nicotinic acetylcholine receptor partial agonist, which means that it activates the brain's nicotinic receptors in a manner similar to nicotine, but with less affinity (effect).
Inclusion of alpha-bungarotoxin, a nicotinic acetylcholine receptor antagonist, or cycloheximide, a protein synthesis inhibitor, during nicotine treatment abolished nicotine-induced podosome rosette formation in the rat cells, suggesting that signalling through the nicotinic acetylcholine receptors and synthesis of new proteins are required for podosome rosette formation.
dorsalis, we report the cloning and characterization of the nicotinic acetylcholine receptor alpha6 cDNA and the expression patterns at different developmental stages and in different tagmata of adult flies using quantitative real-time PCR.
Nicotine acts on the brain by directly binding to and activating a molecule called the nicotinic acetylcholine receptor, which is found on certain brain cells.
Like snake venom, Syn-ake acts as an antagonist of the muscle nicotinic acetylcholine receptor, blocking Na+ release at the post--synaptic membrane, and inhibiting muscle contraction.
The antigenic target is the nicotinic acetylcholine receptor (nAChR) of skeletal muscles.
EnVivo's lead product is an alpha-7 nicotinic acetylcholine receptor agonist that has successfully completed Phase 2b clinical trials in both schizophrenia and Alzheimer's disease.
Cytisine is a partial agonist that binds with high affinity to a subtype of the nicotinic acetylcholine receptor, which is also the primary target of the smokingcessation drug varenicline.