nicotine

(redirected from Nicotine dependence)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Nicotine dependence: nicotine addiction

nicotine

 [nik´o-tēn, nik´o-tin]
a very poisonous alkaloid that in its pure state is a colorless, pungent, oily liquid, having an acrid burning taste. It is a constituent of tobacco, and is also produced synthetically. It is administered orally, intranasally, or by inhalation as an aid to smoking cessation. In water solution, it is sometimes used as an insecticide and plant spray.

Although nicotine is highly toxic, the amount inhaled while smoking tobacco is too small to cause death. The nicotine in tobacco can, however, cause indigestion and increase in blood pressure, and dull the appetite. It also acts as a vasoconstrictor. Researchers link smoking with heart disease, lung cancer, and other diseases.
nicotine poisoning poisoning by nicotine, such as in children who eat cigarettes, workers who handle wet tobacco leaves, or persons who overuse nicotine gums or patches. Symptoms include stimulation followed by depression of the central and autonomic nervous systems and occasionally death due to respiratory paralysis. Called also nicotinism.
nicotine polacrilex nicotine bound to a cation exchange resin; used in nicotine chewing gum as an aid to smoking cessation.

nic·o·tine

(nik'ō-tēn),
A poisonous volatile alkaloid derived from tobacco (Nicotiana spp.) and responsible for many of the effects of tobacco; it first stimulates (small doses), then depresses (large doses) at autonomic ganglia and myoneural junctions. Its principal urinary metabolite is cotinine. Nicotine is an important tool in physiologic and pharmacologic investigation, is used as an insecticide and fumigant, and forms salts with most acids.
See also: tobacco.
[Nicotiana, genus name of botanical source, + - ine]

Nicotine in inhaled tobacco smoke or in smokeless tobacco applied to buccal or nasal mucosa enters the circulation within seconds, causing an increase in heart rate, ventricular stroke volume, and myocardial oxygen consumption, as well as euphoria, heightened alertness, and a sense of relaxation. Nicotine use is powerfully addictive, readily leading to habituation, tolerance, and dependency. Withdrawal from nicotine causes restlessness, irritability, anxiety, difficulty concentrating, and craving for nicotine. Addiction to nicotine is the reason for most tobacco use and is thus directly responsible for the resulting morbidity and mortality.

nicotine

/nic·o·tine/ (nik´o-tēn) (nik´o-tin) a very poisonous alkaloid, obtained from tobacco or produced synthetically; used as an agricultural insecticide, and as an aid to smoking cessation.
nicotine polacrilex  nicotine bound to a cation exchange resin; used in nicotine chewing gum as an aid to smoking cessation.

nicotine

(nĭk′ə-tēn′)
n.
A toxic alkaloid, C10H14N2, that is found in the tobacco plant, constitutes the primary addictive substance in tobacco products, and acts as a stimulant at low doses.

nicotine

[nik′ətēn]
Etymology: Jean Nicot de Villemain, French ambassador to Portugal, 1530-1600
a colorless, rapidly acting toxic substance in tobacco that is one of the major contributors to the ill effects of smoking. It is used as an insecticide in agriculture and as a parasiticide in veterinary medicine. Ingestion of large amounts causes salivation, nausea, vomiting, diarrhea, headache, vertigo, slowing of the heartbeat, and, in acute cases, paralysis of respiratory muscles.

nicotine

Substance abuse A colorless pyridine alkaloid in tobacco Routes Inhalation, skin absorption, ingestion, either accidental or suicidal Clinical Transient CNS stimulation followed by depression or paralysis, nausea, hypersalivation, abdominal pain, vomiting, diarrhea, cold sweats, headache, vertigo, confusion, incoordination, ↓ pulse rate, dyspnea with possible respiratory paralysis and intense vagal stimulation, which may cause cardiac arrest; death occurs 1-4 hrs after ingesting a fatal adult dose–> 60 mg Treatment Emesis, gastric lavage, atropine–Nicotiana tabacum stimulates cholinergic receptors. See Cigarette, Conicotine, Nicotine gum, Passive smoking, Smokeless tobacco, Smoking, Tobacco.

nic·o·tine

(nikŏ-tēn)
A poisonous volatile alkaloid derived from tobacco (Nicotiana spp.) and responsible for many of the effects of tobacco; it first stimulates (small doses), then depresses (large doses) at autonomic ganglia and myoneural junctions. It is an important tool in physiologic and pharmacologic investigation; also used as an insecticide and fumigant.
[Nicotiana, genus name of botanic source, + -ine]

nicotine

A highly poisonous alkaloid drug derived from the leaves of the tobacco plants Nicotiana tabacum and Nicotiana rustica . Large doses are fatal. Very small dose are obtained by inhaling the smoke from burning tobacco and this is done for the sake of the desired slight stimulant and mood-elevating effect and to alleviate nicotine withdrawal symptoms. Nicotine increases the heart rate and raises the blood pressure by narrowing small arteries. This effect can be dangerous. Nicotine, in the doses acquired by smokers, is comparatively harmless but the other constituents of tobacco smoke are responsible for an enormous burden of human disease. Nicotine is dispensed in the form of dummy cigarettes, skin patches and chewing gum so that people who wish to stop smoking may still, for a time, continue to enjoy the perceived advantages. The drug is also used as an insecticide.

nicotine

an alkaloid derived from tobacco.

Nicotine

A colorless, oily chemical found in tobacco that makes people physically dependent on smoking. It is poisonous in large doses.

nicotine

poisonous, volatile alkaloid derived from tobacco; a powerful vasoconstrictor; it promotes hypertension

nicotine

An alkaloid with pharmacological actions similar to those of acetylcholine at autonomic ganglia and skeletal neuromuscular junctions. See acetylcholine; cholinergic.

nic·o·tine

(nikŏ-tēn)
A poisonous volatile alkaloid derived from tobacco (Nicotiana spp.) and responsible for many of its effects; it first stimulates (small doses), then depresses (large doses) at autonomic ganglia and myoneural junctions; an important tool in physiologic and pharmacologic investigation; used as an insecticide and fumigant.

nicotine,

n a poisonous alkaloid found in tobacco and responsible for many of the effects of tobacco. It is first a stimulant (small doses) and then a depressant (larger doses). It is highly addictive.
nicotine gum,
n brand name: Nicorette (nicotine polacrilex); an over-the-counter chewable product containing the chemical nicotine. It is used for tobacco cessation.
nicotine inhaler,
n a prescription inhalation device consisting of a mouthpiece into which a cartridge is inserted to deliver nicotine in gradually diminishing doses over time. It is used for tobacco cessation.
nicotine lozenge,
n an over-the-counter dissoluble tablet that releases nicotine. It is used for tobacco cessation.
nicotine nasal spray,
n a prescription nicotine-containing liquid that the user self-administers through the nose. It is used for tobacco cessation.
nicotine patch (nicotine transdermal system),
n brand names: Habitrol, Nicoderm, Nicotrol, ProStep; an over-the-counter press-on patch that releases nicotine slowly into the body through the skin. It is used for tobacco cessation.
nicotine replacement therapy,
n a tobacco cessation method intended to reduce nicotine cravings and ease the symptoms of withdrawal by substituting another source of nicotine, such as a specially formulated lozenge, gum, nasal spray, inhalant, or skin patch for tobacco products.

nicotine

a very poisonous piperidine alkaloid that in its pure state is a colorless, pungent, oily liquid, having an acrid burning taste. It is a constituent of tobacco and is produced synthetically.

nicotine sulfate
has been used as an anthelmintic but is very poisonous. Signs are dyspnea, tremor and convulsions. Death is due to respiratory paralysis. Has also been used as an insecticide and acaricide. It was once used against sheep scab and is still used against poultry lice.

Patient discussion about nicotine

Q. nicotine patch does anyone know if you can use the patch for smokeless tobacco users,that dont smoke,and how well does it work,what are the side effects,i"ve been using smokeless tobacco for 24 years and would like to stop,tried going cold turkey,but it didnt work,my dr. said i should try the patch,but couldnt tell me if it would work or not.

A. There is really no reason you couldn't try the patch. The problem would be with what dose to start. Usually if people smoke more than 10 cigarettes a day they start with the 21mg but I am not sure how smokeless tobacco relates to cigarettes. Your best bet may be to try the gum as you chew it and then place it between you cheek and gum for a while, similar to dip.

More discussions about nicotine
References in periodicals archive ?
Callers receive a brief intervention for nicotine dependence which is a one-time reactive counseling intervention from a professional counselor and self-help "QuitKit.
It is time for all programs that treat substance dependence to integrate nicotine dependence into their treatment and recovery services.
A study of the psychometric properties of the Fagestrom Test for Nicotine Dependence.
Effects of psychiatric cofactors and nicotine dependence on patterns of smoking withdrawal symptomatology.
Similarly, a cigarette user cannot know how severe his or her nicotine dependence is without measuring it," surmises Sachs.
Finally, the rates of tobacco use, daily tobacco use, and nicotine dependence increased with increasing levels of alcohol consumption and the presence of an AUD.
At the age of 21, homosexuals/bisexuals were at fourfold increased risks of major depression and conduct disorder, fivefold increased risk of nicotine dependence, twofold increased risk of other substance misuse or addiction and six times more likely to have attempted suicide.
Given the abundant medical and scientific evidence about the highly addictive nature of nicotine, and the medical community's recognition of nicotine dependence as a psychiatric disorder, convincing a court that nicotine dependence should be accorded status as a disability within the legal meaning of the term should be possible.
Under the terms of the agreement, BioTie has granted Somaxon an exclusive license in North America to clinically develop, manufacture and market nalmefene for the treatment of impulse control disorders, alcoholism and alcohol abuse and nicotine dependence.
Uses: Nicotine dependence and symptom relief in smoking cessation.
According to Christen Arden, DDS, of the Department of Oral Biology and Indiana University Nicotine Dependence Program, more women than men rely on smoking as a coping response to stress.
Because nornicotine stays in the bloodstream much longer than nicotine, they think it may not only generate AGEs but may also contribute to nicotine dependence.