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cel·lu·lar im·mu·no·de·fi·cien·cy with ab·nor·mal im·mu·no·glob·u·lin syn·the·sis
an ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal.
Synonym(s): Nezelof syndrome
[C. Nezelof, Fr. pathologist, b. 1922]
A rare autosomal recessive immunodeficiency syndrome characterized by underdevelopment of the thymus gland, and thus of cell-mediated immunity, with normal immunoglobulin production.
Nezelof,C., French pathologist, 1922–.
Nezelof syndrome - type of thymic alymphoplasia. Synonym(s): cellular immunodeficiency with abnormal immunoglobulin synthesis