NEK3

(redirected from Never in mitosis A-related kinase 3)

NEK3

A gene on chromosome 13q14.2-q21.1 that encodes a NEK serine/threonine protein kinase that influences neuronal morphogenesis and polarity by regulating acetylation within the microtubules of neurons. STK1 has prolactin-dependent interaction with PXN, PRLR, VAV1 and VAV2, and has been implicated in prolactin-mediated cytoskeletal reorganisation and motility of breast cancer cells.
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