Indeed, Rosin and Martin (1981) reported significant reductions in uptake of biogenic amine
neurotransmitters into synaptosomes after exposure to Aroclor mixtures, whereas Mariussen and Fonnum (2001) recently reported that only noncoplanar PCB congeners inhibited uptake of labeled DA into striatal synaptosomes.
Inhibition of reuptae allows buildup of
neurotransmitters in the synapse and activation of the auto-receptors, leading to a decrease in firing activity, said Dr Blier.
Neurotransmitters are chemicals that permit the passage of signals within the brain.
Serotonin, famed as the target of Prozac and other antidepressants, acts as a
neurotransmitter, relaying signals from one brain cell to the next.
In Alzheimer's disease, however, there is a block in the transport system which carries the
neurotransmitters to the axon terminals.
The
neurotransmitters and hormones are less effective when their circadian pattern is altered.
It was known that during a child's early brain development, exposure to lead during synaptogenesis affects the release of these critical
neurotransmitters but the reason was unclear.
Researchers have been missing a key piece of the taste puzzle: the identity of the messenger, known as a
neurotransmitter, that sends information from taste buds to the nerve fibers.
Drugs that seem to have efficacy in depression generally enhance levels of monoamine
neurotransmitters such as serotonin or norepinephrine.
Amphetamines such as Dexedrine and Ritalin, known for calming hyper children, boost the flow of
neurotransmitters.
Chapters by distinguished international basic and clinical scientists in the field of stress and
neurotransmitters offer new insights into stress, stress-related disorders, and their future stressor-specific treatment.
The enzyme can be found in higher concentrations in glial cells and monoamine-releasing neurons, where it breaks down the
neurotransmitters serotonin, dopamine, and norepinephrine.
