We thought it might be involved in memory problems of AD because it is a master regulator of neurotransmission
and its brain levels are decreased in the disease," said Moustapha Cisse.
The bottom line -- Gabapentin and pregabalin reduce neurotransmission
in activated pain pathways by binding the [[alpha].sub.2][delta] subunit of VSCCs.
Searching for the molecular basis of memory loss, the team discovered the importance of PI3-kinase by studying a type of neurotransmission
called long-term depression (LTD).
They may have an indirect effect on serotonin via the suppression of inhibitory GABAergic neurotransmission
Prenatal smoke exposure-induced low MAO-A activity in foetal life may dysregulate brain neurotransmission
, creating a potential vulnerability to develop behavioural disorders later in life.
Deficient serotonergic neurotransmission
has been hypothesized as a cause of major depression for 30 years, and postmortem studies have linked serotonergic dysfunction in the ventral prefrontal cortex to suicide, said Dr.
The study has linked specific variants of two genes that regulate dopamine and serotonin neurotransmission
to risk-taking in financial investment decisions.
The study used positron emission tomography to monitor regional cerebral blood flow and dopaminergic neurotransmission
during the same session in six patients with DSM-IIIR-diagnosed schizophrenia and six age-, sex-, and handedness-matched controls who had no psychiatric history.
MADRID -- Impulsivity, a core component of a number of psychiatric conditions, appears to be related to serotonin neurotransmission
and may be influenced in part by a specific receptor gene, Dr.
Several earlier studies have suggested that violent and psychotic behaviour are associated with alterations in glucose metabolism and opioidergic neurotransmission
. The new findings support the idea of abnormal opioid system function being a factor underlying psychopathy.
Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission
. Prog Neuropsychopharmacol Biol Psychiatry.
At the physiological level, the researchers found impaired striatal dopamine neurotransmission