Neuromuscular junction

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Related to Neuromuscular junctions: myofibril


a place of meeting or coming together. adj., adj junc´tional.
atrioventricular junction in the conduction system of the heart, the junction between the atrioventricular node and the nonbranching portion of the bundle of His.
cementoenamel junction the line at which the cementum covering the root of a tooth meets the enamel covering the crown.
gap junction a narrowed portion of the intercellular space, containing channels linking adjacent cells and through which can pass ions, most sugars, amino acids, nucleotides, vitamins, hormones, and cyclic AMP. In electrically excitable tissues the gap junctions serve to transmit electrical impulses via ionic currents and are known as electrotonic synapses; they are present in such tissues as myocardial tissue.
myoneural junction (neuromuscular junction) the site of junction of a motor nerve fiber and a skeletal muscle fiber that it innervates. The discoid expansion of the terminal branch of the axon forms the motor end plate, the neurotransmitter that diffuses across the synapse is acetylcholine.
sclerocorneal junction limbus (def. 2).
ureteropelvic junction the area where the renal pelvis meets the ureter.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

my·o·neu·ral junc·tion

the synaptic connection of the axon of the motor neuron with a muscle fiber. See: motor endplate.
Farlex Partner Medical Dictionary © Farlex 2012


(junk'shun) [L. junctio, a joining]
The place of union or coming together of two parts or tissue layers.

amelodentinal junction

Dentinoenamel junction.

atrioventricular junction

The area of cardiac conduction pathway connecting the AV node with the atrioventricular bundle.

cementodentinal junction

The interface of dentin and cementum of the tooth. Synonym: dentinocemental junction

cementoenamel junction

The line around the tooth that marks the boundary between the crown and root of the tooth; the interface between enamel and cementum.

costochondral junction

The articulation or meeting place of the bony rib and its costal cartilage.

cervicomedullary junction

The nexus between the most superior part of the spinal cord and the medulla oblongata of the brainstem.

dentinocemental junction

Cementodentinal junction.

dentinoenamel junction

The plane or interface between the dentin of the tooth and the enamel crown; histological sections show it to be a scalloped boundary at the site of the basement membrane which separated the cell layers that formed the calcified enamel and dentin. Synonym: amelodentinal junction

dentogingival junction

The interface and zone of attachment between the gingiva and enamel or cementum of the tooth. It holds in place the junctional or attachment epithelium.

interneuronal junction


liquid junction

The point in a potentiometric reference electrode measurement system at which the reference solution makes contact with the test solution. An example is pH reference electrode.

mucocutaneous junction

The junction between the skin and a mucous membrane.

mucogingival junction

A scalloped, indistinct boundary between the gingiva and the oral mucosa on the alveolar process. The coral color of gingiva may be contrasted with the more vascular oral mucosa. Also called the mucogingival line.
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myoneural junction

The axon terminal of a motor neuron, synaptic cleft, and sarcolemma of a muscle cell. Synonym: neuromuscular junction
See: illustration

neuromuscular junction

Myoneural junction.

saphenofemoral junction

The merging of the saphenous and femoral veins in the inguinal region.

sclerocorneal junction

The meeting point between the sclera and the cornea marked on the external surface of the eyeball by the outer scleral sulcus.
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SQUAMOCOLUMNAR JUNCTION: Squamocolumnar junction of the distal esophagus (seen endoscopically)

squamocolumnar junction

1. The point in the cervical canal at which the squamous and columnar epithelia meet. As most cervical cancers begin in this area, it is important to obtain cells from this location for the Pap test.
2. The point above the lower esophageal sphincter where the squamous epithelium of the esophagus and the columnar epithelium of the stomach meet.
Synonym: transition zone. See: illustration

tight junction

A part of the junctional complex at the lateral interface between epithelial cells; also called zonula occludens.
Medical Dictionary, © 2009 Farlex and Partners

neuromuscular junction

the area of contact between a MOTOR NEURON and a MUSCLE FIBRE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Neuromuscular junction

The site at which nerve impulses are transmitted to muscles.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
botulinum, A, B, [C.sub.1], [C.sub.2], D, E, F, and G, all of which interfere with neural transmission by blocking the release of acetylcholine at the neuromuscular junction (NMJ) and reduce muscle activity.
Caption: Figure 6: Distribution of mEJPs amplitudes recorded at muscle fiber 6 and 7 neuromuscular junctions from transgenic Drosophila melanogaster larvae.
Since the 1970s, researchers have come up with numerous ways to simulate the neuromuscular junction in the lab.
Terminal sprouting in mouse neuromuscular junctions poisoned with botulinum type A toxin: morphological and electrophysilogical features.
The CD8-GFP line was used to visualize the branching of the synaptic terminals at the neuromuscular junction (NMJ).
Physiological activity-dependent ultrastructural plasticity in normal adult rat neuromuscular junctions. Bio.
Investigators at Regeneron Pharmaceuticals, a biotech firm in Tarrytown, N.Y., discovered MuSK last year and noticed that, in adult mice, it is normally found only at neuromuscular junctions. The researchers have now created mice lacking MuSK.
The findings regarding the trapezius indicated that some ALS onsets could be initiated by a 'dying back' process, with destruction of neuromuscular junctions (NMJs) before motor neurons.
(4) Acetylcholinesterase inhibition results in accumulation of acetylcholine and overstimulation of acetylcholine receptors in synapses of the autonomic nervous system, CNS and neuromuscular junctions.
Fifty-four chapters are organized into eight sections: historical and present approaches in the clinic and laboratory to diagnosing neuromuscular problems, two chapters on infantile hypotonia and arthrogryopsis, disorders of motor neurons, disorders of the peripheral nerves, disorders of neuromuscular junctions, myopathies, special clinical problems associated with neuromuscular disorders, and principles of treatment, with this last section addressing acute therapy, long-term management and rehabilitation, and outcome measures.

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