neuromuscular blocking agents


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neu·ro·mus·cu·lar block·ing a·gents

a group of drugs that prevents motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine (for example, D-tubocurarine, mivacurium, and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to acetylcholine (for example, succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles.

neu·ro·mus·cu·lar block·ing a·gents

(nūrō-mŭskyū-lăr bloking ājĕnts)
Drugs that prevent motor nerve endings from exciting skeletal muscle.
References in periodicals archive ?
It's important to note that neuromuscular blocking agents have made surgery considerably safer and more effective since their introduction several decades ago says Professor Blobner.
Use of sedating drugs and neuromuscular blocking agents in patients requiring mechanical ventilation for respiratory failure: a national survey.
In 69.1% cases neuromuscular blocking agents (NMBAs) especially atracurium and in 12.1% cases latex were the most frequently involved agents implicated for anaphylaxis according to the most recent French epidemiological survey.
Zhang, "[Clinical study of early use of neuromuscular blocking agents in patients with severe sepsis and acute respiratory distress syndrome]," Zhonghua wei zhong bing ji jiu yi xue, vol.
This study was aimed to determine the efficacy of rocuronium, a newer nondepolarizing neuromuscular blocking agent, compared with vecuronium for rapid sequence intubation.
Adverse effects of neuromuscular blocking agents based on yellow card reporting in the U.K.: are there differences between males and females?
Sugammadex sodium injection is Merck's investigational agent for the reversal of neuromuscular blockade (NMB) induced by rocuronium or vecuronium (neuromuscular blocking agents).
RSI also has risks; using neuromuscular blocking agents has potential complications because of the removal of spontaneous respiratory effort and possibly the loss of airway patency under certain circumstances.
The costs of expensive items such as volatile agents, packed red cells, and neuromuscular blocking agents were underestimated whereas the costs of inexpensive items, such as plastic disposable equipment, non-steroidal anti-inflammatory drugs, opioids and sedatives, were overestimated (Figure 1).

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