neurofilament

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Related to Neurofilaments: Neurofilament proteins

neurofilament

 [noor″o-fil´ah-ment]
any of the slender, fibrillar elements which, along with the neurotubules, forms a neurofibril.

neu·ro·fil·a·ment

(nū'rō-fil'ă-ment),
A class of intermediate filaments found in neurons.

neurofilament

(no͝or′ə-fĭl′ə-mənt, nyo͝or′-)
n.
Any of the long, fine threads that make up a neurofibril.

neu′ro·fil′a·men′tous (-mĕn′təs) adj.

neu·ro·fil·a·ment

(nūr'ō-fil'ă-mĕnt)
A class of intermediate filaments found in neurons.
References in periodicals archive ?
Jucker and his colleagues monitored the development of neurofilament concentration in these individuals from year to year.
Post 19 h myelin loss, enlargement in the endoplasmic reticulum, swelling in the mitochondria, and clustering in the neurofilaments were observed.
CSF neurofilament heavy-chain (NfH) values were found to correlate with EDSS in a 17-year follow-up period, to reflect chronic axonal destruction (65), and also to estimate the amount of brain and spinal cord atrophy on MRI (66).
Connor et al., "Neurofilaments is a protein phosphatase-1-binding protein associated with neuronal plasma membrane and post-synaptic density," The Journal of Biological Chemistry, vol.
Caption: FIGURE 3: Sections of the external segment of the meatus acusticus externus cartilagineus (MAEC) stained with Masson's trichome staining ((a)-(d)) and immunostained for demonstration of neurofilaments ((e)-(g)).
Therefore, axon damage was detected using SMI-32 antibody, which recognizes nonphosphorylated neurofilaments [30].
Neurofilaments are highly abundant proteins in neurons and are found in the axons of all neurons.
A primary antibody against neurofilament 68 (NF681: 400, Novusbio, Littleton, CO, USA) was applied to the slices overnight at 4[degrees]C.
The challenge of clivorine in PC12 cultures showed robust decrease of markers for neuronal differentiation, including (i) NGF-induced neurite outgrowth; (ii) mRNAs and proteins encoding for neurofilaments; and (iii) downstream signaling of NGF, i.e.
Immunohistochemical studies were positive for chromogranin, synaptophysin and neurofilaments, but negative for desmin and CD99.
But with millions of cells, all carrying the human disease, to work with, Zhang's research group discovered the source of the tangles in the protein subunits that compose the neurofilaments.
Neurofilaments are defined as the long flexible protein polymers that are transported along the axonal process between neurons.