neuroendocrine tumour


Also found in: Acronyms.

neuroendocrine tumour

An endocrine tumour neoplasm with a characteristic morphology, often composed of sheets and clusters of round blue cells with granular chromatin and an attenuated rim of poorly demarcated cytoplasm.
 
Clinical findings
NETs present with vague, nonspecific symptoms, including abdominal pain, nausea, weight loss and, rarely, obstructive symptoms; only 10% present with a carcinoid syndrome due to high circulating neuroendocrine hormones, in particular serotonin (5-HT), which causes flushing, diarrhoea, asthma and tricuspid regurgitation.

Examples
Carcinoids, small cell carcinomas, medullary carcinoma of thyroid, Merkel cell tumour, cutaneous neuroendocrine tumours, pancreatic islet cell tumours, pheochromocytoma.

Neuroendocrine tumour
Low grade—Typical carcinoid.
Intermediate grade—Atypical carcinoid.
High grade—Large cell: neuroendocrine tumour; small cell: lung cancer.
References in periodicals archive ?
Recently, updated guidelines for the management of patients with digestive neuroendocrine tumours and current diagnostic procedure have been published [3, 4].
Symptoms of gastrointestinal neuroendocrine tumours (GI NETs)
Dr Rawat said, "NeuroEndocrine Tumour is an abnormal growth of Neuroendo cells which are present in bodies.
Under the contract, both companies will assess the efficacy of combining somatostatin analogues' neuroendocrine tumour targeting capabilities with the cell-killing potential of Areva Med's lead-212 radionuclide.
Summary: Bollywood actor Irrfan Khan was diagnosed with a neuroendocrine tumour in March
Summary: Singh is urging people to stop speculating about Khan's health, who is currently seeking treatment for a neuroendocrine tumour
Summary: The actor on Friday revealed that he has been diagnosed with a neuroendocrine tumour
Actor Irrfan Khan has confirmed he has been diagnosed with a neuroendocrine tumour, which is described as a rare condition that develops from cells of the endocrine (hormonal) system that are found in organs including the stomach, bowel and lungs.
American Joint Commission on Cancer (AJCC) adopted a tumour, node, metastases (TNM) based staging system for all anatomic sites that is parallel to the TNM system established by European Neuroendocrine Tumour Society (ENETS).
The sequel will be Khan's first project after he was diagnosed with a neuroendocrine tumour in March last year.
Several organizations including the American Joint Committee on Cancer (AJCC), European Neuroendocrine Tumour Society (ENETS), WHO and the Union for International Cancer Control (UICC) have individually or jointly proposed staging systems for some of the most common types of NETs.

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