(redirected from Neprylisin)


A metallomembrane endopeptidase enzyme, a major constituent of kidney brush-border membranes. Also found in the brain. Identical to common acute lymphoblastic leukemic antigen.
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Our urine proteomic results show proteins related to inflammation and vasoactive pathways, such as osteopontin, VCAM, neprylisin, and kininogen, that are differentially expressed in the cohorts studied.
(2005) Neprylisin decreases uniformly in Alzheimer's disease and in normal aging.