Nephrotic syndromes


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Related to Nephrotic syndromes: nephritic syndrome

Nephrotic syndromes

A collection of symptoms that result from damage to the filtering units of the kidney (glomeruli) causing severe loss of protein from the blood into the urine.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about Nephrotic syndromes

Q. Q. I want to know about urine protein creatine ratio in diagnosing nephrotic syndrome. Please explain interms of unit such as mg/mg or mmol/mg. Normal range, nephrotic range with good referrence.

A. Nephrotic syndrome is defines as a damage to the kidneys, in which there is a leak of large amounts of protein (over 3.5 grams of protein / 24 hours urine output) from the blood to the urine. Protein loss causes low protein count in the blood (hypoalbuminemia) and edemas (excess fluid in the interstitial cavity which is between the cells, causes leg swelling most often, and also in the adbomen and around the eyes).

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References in periodicals archive ?
Evaluating an optimal cut-off value of IgG urinary loss before a possible administration of Rituximab could significantly contribute to a patient individualized treatment approach in refractory nephrotic syndrome.
Kamei et al., "Rituximab in refractory nephrotic syndrome," Pediatric Nephrology, vol.
Edefonti et al., "Short-term effects of rituximab in children with steroid- and calcineurin-dependent nephrotic syndrome: a randomized controlled trial," Clinical Journal of the American Society of Nephrology, vol.
Ghiggeri, "Anti-CD20 antibodies for idiopathic nephrotic syndrome in children," Clinical Journal oftheAmerican Society of Nephrology, vol.
We will focus on major therapeutic advances in iMN, MCD, and FSGS as causes for primary nephrotic syndrome in adults.
Indications for immunosuppressive therapy for iMN therefore depend on the level of proteinuria (>4g/24h), rate of GFR decline, and complications of the nephrotic syndrome [1].
A Dutch RCT investigated 26 patients with nephrotic syndrome who had a normal glomerular filtration rate (GFR).
Minimal change disease (MCD) accounts for 10-15% of patients with idiopathic nephrotic syndrome in adults [32].
Effect of WPC on Plasma Biomarkers in Rats with PAN-Induced Nephrotic Syndrome. The total bilirubin level was not different in the PAN group when compared with the Sham or WPC groups.
Effect of WPC on Kidney Dysfunction in Rats with PAN-Induced Nephrotic Syndrome. Higher urinary protein level was measured in the PAN group than in the Sham group.
As shown, in Figure 2(b), the WPC group showed significantly reduced AQP2 protein and mRNA expression in the PAN-induced nephrotic syndrome model.
Kazi JI, Mubarak M, Ahmed E, Akhter F, Naqvi SA, Rizvi SA.Spectrum of glomerulonephritides in adults with nephrotic syndrome in Pakistan.