nephrogenic adenoma(redirected from Nephrogenic metaplasia)
a benign tumor of the urinary bladder or urothelium, composed of glandular structures resembling renal tubules.
nephrogenic adenomaA benign lesion which is more common in women and arises in urothelium-lined structures, especially the bladder, which often contains scant amounts of crystalloid material. It is regarded as a metaplastic response to mechanical trauma—e.g., recurrent UTIs, stones, diverticuli, urinary tract instrumentation, ulcers, infection, ureteric stents, intravesical therapy and open bladder surgery.
Prostate adenocarcinoma (tubular structures), clear cell (hobnailing) carcinoma, in situ adenocarcinoma.
Presence of tubules, cords, and signet ring-like cells; prominent nucleoli; muscle involvement; blue-tinged mucinous secretions; focal prostate specific antigen and PSAP positivity; and negative staining for high molecular weight CK (34betaE12).