Antiangiogenic and antimetastatic properties of Neovastat
(Ae-941) an orally active extract derived from shark cartilage.
Washington, May 27 (ANI): Shark cartilage extract, AE-941 or Neovastat, has shown no benefit as a therapeutic agent when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer, say researchers at The University of Texas MD Anderson Cancer Center.
A unique and important aspect about this shark cartilage study was that this product, Neovastat, was never sold over-the-counter, unlike other shark cartilage compounds previously studied.
Another NCI-sponsored study evaluating Neovastat
(AE-941), an angiogenesis inhibitor derived from ultrafiltration of liquid dogfish shark cartilage, is ongoing.
Its experimental drug, called Neovastat
, is "not like the powdered cartilage that you find in health food stores;' explains company spokesman Paul Burroughs.
has been developed as a pharmaceutical, going through phase I and II studies, he explained.