Negri bodies


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Related to Negri bodies: rabies, Guarnieri bodies

Ne·gri bod·ies

(nā'grē),
eosinophilic, sharply outlined, pathognomonic inclusion bodies (2-10 mcm in diameter) found in the cytoplasm of certain nerve cells containing the virus of rabies, especially in Ammon horn of the hippocampus.

Ne·gri bod·ies

(nā'grē bod'ēz)
Eosinophilic, sharply outlined, pathognomonic inclusion bodies (2-10 mcm in diameter) found in the cytoplasm of some nerve cells containing the virus of rabies, especially in Ammon's horn of the hippocampus.

Negri,

Adelchi, Italian physician, 1876-1912.
Negri bodies - pathognomonic inclusion bodies found in the cytoplasm of certain nerve cells containing the rabies virus.Synonym(s): Negri corpuscles
Negri corpuscles - Synonym(s): Negri bodies

Ne·gri bod·ies

(nā'grē bod'ēz)
Eosinophilic, sharply outlined, pathognomonic inclusion bodies found in the cytoplasm of some nerve cells containing the rabies virus.
References in periodicals archive ?
Retrograde transport of rabies virus within neuronal cells and considerable hijacking of TLR3 receptors are the reasons to produce granular shape Negri bodies (Menager et al., 2009).
Antemortem diagnosis may be made by using corneal impressions, viral isolation from saliva and cerebrospinal fluid, serum and cerebrospinal fluid for rabies antibody titers, and skin biopsy of the highly innervated hair-covered area of the neck for rabies fluorescent antibody testing for the rabies antigen.[33] Findings from neck skin biopsies are positive in 50% to 60% of patients with rabies.[1,34,35] The Negri bodies are eosinophilic intracytoplasmic viral inclusion bodies in infected neurons.
Diagnostic tests identified Negri bodies by staining with hematoxylin and eosin and lyssavirus antigens by dFAT in brain and spinal cord tissue (Figure 1).