negative control

neg·a·tive con·trol

regulation of an enzyme activity by an inhibitor of that enzyme or regulation of a protein by repression of transcription.

negative control

Lab medicine
A specimen or sample known to lack a particular substance, which is used as a standard for measuring a tested substance’s effect.

Molecular biology
The downregulation of gene transcription in response to the binding on DNA of negative regulatory elements.
References in periodicals archive ?
Serum level of IL-4 was increased in all experimental groups in two weeks compared to the negative control (Immunological suppress) group (23.66 [+ or -] 4.04 pg / ml)(Table 1).
Some participants in these groups displayed high negative conditional control between the samples and the X stimuli, and this negative control was related to a low probability to establish equivalence relations.
The blank control group, negative control group (transfected with miR-21 negative sequences), miR-21 inhibitor group (transfected with miR-21 inhibitors), miR-21 mimic group (transfected with miR-21 mimics) and PDCD4 siRNA group (transfected with PDCD4 siRNAs) were established.
Table 1 presents the Mitotic Indices obtained for the Positive Control, Negative Control and Jatoba Control treatment groups at concentrations of 0.5; 1.0 and 1.5 mg/mL, and the Simultaneous Treatment at concentrations of 0.5; 1.0 and 1.5 mg/mL, assessed at the exposure time of 24 hours.
The percent reduction of resazurin to resorufin was calculated in comparison to a negative control which consists of media + alamarBlue with no cells.
The nine studies that used negative control outcomes chose outcomes that were not anticipated to be related to exposure (McClellan, McNeil, and Newhouse 1994; Redelmeier, Scales, and Kopp 2005; Jackson et al.
Anti lg M coated strips were taken and numbered as 1, 2, 3 after considering 1st and 2nd wells at negative control and positive control.
In addition, the company said the submission included a study of the concordance of positive and negative control Reference Panel Specimens with a blinded cytological interpretation when the specimens were processed and read at multiple, independent laboratories.
1% Phenol served as positive and cells as negative control respectively.
Six 10- to 35-day-old pigs were randomly assigned to a PEDV-infected group (pigs 1-5) or a negative control group (pig 6).
Group 1 represented the negative control group, which received 1 mL/100 g body weight distilled water.