natriuretic peptide(redirected from Natriuretic factor)
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Related to Natriuretic factor: Atriopeptin
a·tri·al na·tri·u·ret·ic pep·tide (ANP),
a 28-amino acid peptide (α-ANP) derived from cardiac atria, several smaller fragments of α-ANP, and a dimer of α-ANP with 56 amino acids (β-ANP) that are present in plasma in heart failure. Among other actions, ANP promotes renal salt and water excretion, increases capillary function, and decreases arterial pressure and the secretion of renin, angiotensin, aldosterone, and antidiuretic hormone.
Farlex Partner Medical Dictionary © Farlex 2012
Any peptide that stimulates the kidneys to excrete salt and water.
See also: peptide
Medical Dictionary, © 2009 Farlex and Partners
natriuretic peptideA PEPTIDE present in the blood and raised in quantity in people with long-term (chronic) HEART FAILURE. It arises in the upper chambers of the heart, probably as a result of stretching, and causes blood vessels to widen and the output of urine to increase. By increasing output of urinary sodium and, with it, water, it helps to relieve the OEDEMA that is a feature of HEART FAILURE. Also known as atrial natriuretic factor. B-type natriuretic peptide is released by ventricular muscle cells and is used as a therapeutic agent in heart failure. It is also used as a biomarker for differential diagnosis of breathlessness and for preclinical assessment of heart failure.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005