natriuretic peptide

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Related to Natriuretic factor: Atriopeptin

a·tri·al na·tri·u·ret·ic pep·tide (ANP),

a 28-amino acid peptide (α-ANP) derived from cardiac atria, several smaller fragments of α-ANP, and a dimer of α-ANP with 56 amino acids (β-ANP) that are present in plasma in heart failure. Among other actions, ANP promotes renal salt and water excretion, increases capillary function, and decreases arterial pressure and the secretion of renin, angiotensin, aldosterone, and antidiuretic hormone.

natriuretic peptide

Any peptide that stimulates the kidneys to excrete salt and water.
See also: peptide

natriuretic peptide

A PEPTIDE present in the blood and raised in quantity in people with long-term (chronic) HEART FAILURE. It arises in the upper chambers of the heart, probably as a result of stretching, and causes blood vessels to widen and the output of urine to increase. By increasing output of urinary sodium and, with it, water, it helps to relieve the OEDEMA that is a feature of HEART FAILURE. Also known as atrial natriuretic factor. B-type natriuretic peptide is released by ventricular muscle cells and is used as a therapeutic agent in heart failure. It is also used as a biomarker for differential diagnosis of breathlessness and for preclinical assessment of heart failure.
References in periodicals archive ?
Those granules, in the myocytes of the auricles and in the atria, contain a peptide hormone called atrial natriuretic factor (ANF).
mRNA levels of atrial natriuretic factor (ANF, A), matrix metalloproteinase (MMP)-9 (B) and MMP-13 (C) in cardiomyocytes with endothelin-induced hypertrophy treated with etanercept assessed by qRT-PCR.
Trachte, "Atrial natriuretic factor receptors and signal transductionmechanisms," Pharmacological Reviews, vol.
Derangements of sympathetic nervous system simulation of kidneys, production of digoxin-like peptides, and excess natriuretic factors have all been implicated in CSW.
C, Measurement of atrial natriuretic factor (ANF) and brain natriuretic peptide (BNP) mRNA levels in WT and TG hearts at 2 and 5 months of age.
They described, for example, two ofthe new recombinant proteins designed to help heart patients: atrial natriuretic factor (ANF), a hormone capable of reducing blood pressure and water retention in people suffering from congestive heart failure and hypertension; and tissue plasminogen activator (tPA), a clot-dissolving enzyme that can reduce tissue damage after sudden heart attacks.
Atrial natriuretic factor (ANF), a hormone discovered in 1981, controls salt and water balance.
But while artificial hearts may adequately pump blood, or in the case of the Tin Man make a ticking sound, they can't do something that natural hearts do -- produce a hormone called artrial natriuretic factor (ANF).
[4] Nonstandard abbreviations: ANP, atrial natriuretic peptide; ANF, atrial natriuretic factor; BNP, brain or B-type natriuretic peptide; CNP, C-type natriuretic peptide; HF, heart failure; NT-proBNP, N-terminal pro-BNP; DMEM, Dulbecco modified Eagle medium; FBS, fetal bovine serum; HRP, horseradish peroxidase; Ben-gal, benzyl 2-acetamido-2-deoxy-a-D-galactopyranoside.
Atrial natriuretic factor in normal subjects and heart failure patients: plasma levels and renal, hormonal and hemodynamic responses to peptide infusion.