naive

naïve

 [nah-ēv´]

not previously exposed to therapy or treatment.

naive

or

naïve

(nī-ēv′, nä-) also

naif

or

naïf

(nī-ēf′, nä-)

adj.

Not having experienced or been subjected to something, as:

a. Not previously subjected to experiments: testing naive mice.

b. Not having previously taken or received a particular drug: patients naive to antipsychotic medication.

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na·ive′ly adv.

na·ive′ness n.

Immunology Referring to a person or an immune system which has not been previously exposed to a particular antigen and thus doesn’t form antibodies against the antigen
Vox populi Innocent, unsophisticated, artless, ingenuous, unworldly, trusting