GRIN3B

(redirected from NR3B)

GRIN3B

A gene on chromosome 19p13.3 that encodes a subunit of N-methyl-D-aspartate (NMDA) receptors, which belong to the glutamate receptor channel superfamily. NMDA receptors consist of multiple subunits arranged to form a ligand-gated ion channel, which play a key role in long-term potentiation and the plasticity of synapses (central to memory and learning). GRIN3B forms a complex with GRIN1 and GRIN2A.
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References in periodicals archive ?
Yuzaki, "Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability," Molecular Brain Research, vol.
ERR[alpha] belongs to the NR3B orphan nuclear receptor subgroup, which consists of ERR[alpha], ERR[beta], and ERR[gamma] (Hong et al.
(6) NR3A and NR3B receptor subunits are widely distributed in brain.