nephronophthisis(redirected from NPH, NPHP)
wasting disease of the kidney substance.
familial juvenile nephronophthisis a progressive hereditary kidney disease marked by anemia, polyuria, renal loss of sodium, progressing to chronic renal failure, tubular atrophy, interstitial fibrosis, glomerular sclerosis, and medullary cysts.
nephronophthisisA progressive tubulo-interstitial kidney disorder histologically characterised by modified tubules, thickened basement membrane, interstitial fibrosis and, in advanced cases, medullary cysts.
Chronic renal failure, anaemia, polyuria, polydipsia, isosthenuria and growth retardation.