These included the International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT), (23) the Nordic Diltiazem (NORDIL) study, (24) the Australian National Blood Pressure Study 2 (ANBP2), (28) the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial, (26) the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial, (29) and the Irbesartan in Heart Failure with Preserved Systolic Function (I-PRESERVE) study.
Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality, in hypertension: the Nordic Diltiazem (NORDIL) study.
These were the International Nifedipine-GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT), the Nordic Diltiazem Study (
NORDIL), and the second Swedish Trial in Old Patients with Hypertension (STOP-Hypertension-2).