NOD2

(redirected from NOD2BPSORAS1 OTTHUMP00000164224 CARD15 OTTHUMP00000236088 IBD1)

NOD2

A gene on chromosome 16q21 of the Nod1/Apaf-1 family that encodes a protein with two caspase recruitment (CARD) domains, which is expressed on white cells in the peripheral blood and activates NFKB protein in response to intracellular bacterial lipopolysaccharides. NOD2 mutations are linked to Crohn’s disease and Blau syndrome.