NO synthase


Also found in: Encyclopedia.

NO syn·thase

(sin'thēs),
Abbreviation for nitric oxide synthase.
References in periodicals archive ?
Differential effects of serotonin reuptake inhibitors on erectile responses, NO-production, and neuronal NO synthase expression in rat corpus cavernosum tissue.
Quantification of mRNA for endothelial NO synthase in mouse blood vessels by real-time polymerase chain reaction.
Western blot analysis and measurement was performed for inducible NO synthase (iNOS) and nNOS release as previously described (30).
The primary vasodilating mediator is nitric oxide, which as a result of biosynthesis is extracted from the amino acid of L-arginine with the participation of the endothelial nitric oxide synthase (NO synthase) enzyme [11].
NO is an inorganic free radical with a diversity of physiological functions, synthesized from the amino acid L-arginine by three isoforms of the NO synthase enzyme (NOS; e.g., NOSI, NOSII, and NOS III) (13,14).
Murad, "[Ca.sup.2+]/calmodulin-dependent NO Synthase type I: A biopteroflavoprotein with [Ca.sup.2+]/calmodulin-independent diaphorase and reductase activities," Biochemistry, vol.
Zhou et al., "The protective action of ketanserin against lipopolysaccharide-induced shock in mice is mediated by inhibiting inducible NO synthase expression via the MEK/ERK pathway," Free Radical Biology and Medicine, vol.
In human body they are classified by tissue origin as: neuronal NO synthase (nNOS), endothelial NO synthase (eNOS) and NO synthase of immune cells origin (iNOS).
Nitric oxide (NO) has been found to be closely associated with the pathogenesis of COPD, the alteration of NO synthase (NOS) expression need to be revealed.
So it is possible adiponectin effect on expression of NO synthase isoforms in endometrium especially stromal cells and decrease NO level in stromal cells cultured and improves inhibition of endometriosis progresses.
Green, et al., Requirement for transcription factor IRF-1 in NO synthase induction in macrophages, Science.
Studies have shown that hemorrhagic shock leads to enhanced production of NO as well as increased tissue NO synthase (NOS) activity.34