In the proposed hierarchical routing, every node contains an NNT
as a routing table.
By Pfizer's own admission, 100 people have to take the drug for more than three years for one to benefit, an NNT
Results: Bivariate analysis indicated that neonates with NNT
were more likely to have been delivered outside a health facility, on an unclean surface, without use of gloves, or by unskilled attendants.
While the NNT
does have well-recognised benefits over RRR, it is certainly hyperbole to call use of the RRR statistic 'unethical'.
Number needed to treat (NNT
) and number needed to harm (NNH)-2 tools of evidence-based medicine--can help answer these questions.
Such a low NNT
makes a compelling case for this treatment approach.
LIFTCo appealed the decision and the case went before a planning inspectorate.
In terms of numbers needed to treat (NNT
), BALANCE showed that seven bipolar patients would need to receive combination therapy for 2 years instead of valproate in order for there to be one fewer relapse; that's a very favorable NNT
The numbers needed to treat (NNT
) were "particularly disturbing," in Dr.
Indeed, the number of such patients who needed to be treated (NNT
) with the third-generation bisphosphonate to prevent one additional case of osteopenia at 3 years was just 4.5 in the Austrian Breast and Colorectal Cancer Study Group trial 12 (ABCSG-12), Dr.
The IMPROVE-IT trial1 offers the best supportive evidence for the use of ezetimibe, but still finds only a 2% absolute risk reduction (ARR) in a composite endpoint (cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization [greater than or equal to] 30 days after randomization, or nonfatal stroke), equating to a number needed to treat (NNT
) of 50.