NMDA receptor


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Related to NMDA receptor: AMPA receptor, NMDA receptor antagonist

NMDA re·cep·tor

a type of glutamate receptor that participates in excitatory neurotransmission and also binds N-methyl-d-aspartate; may be particularly involved in the cell damage observed in individuals with Huntington disease.

NMDA receptor

(ĕn′ĕm′dē′ā′)
n.
A brain receptor activated by glutamate, which when excessively stimulated may cause cognitive defects in Alzheimer's disease.
References in periodicals archive ?
Targeting the NMDA receptor subunit NR2B for the treatment of neuropathic pain.
"Because these receptors are so similar in structure, it was assumed that they function in much the same way, but when we altered the dimer interface, the site where two subunits come together within each pair, we found that the NMDA receptor works just the opposite of the way that the AMPA receptor works," points out Popescu.
and other countries) have shown xenon exerts a neuroprotective effect by preventing excess glutamate from interacting with its NMDA receptor.
Prenatal exposure of testosterone prevents SDN-POA neurons of postnatal male rats from apoptosis through NMDA receptor. J.
AV-101 (4-Cl-KYN) is an investigational, oral NMDA receptor glycine site antagonist with potential to be a treatment for multiple CNS indications with high unmet need.
Therefore, it appears that NMDA receptor antagonists may be key to developing a new generation of improved treatments for major depression.
In the present study, we investigated the role of astaxanthin on calcium homeostasis throughout calcium channels, calcium binding proteins and NMDA receptor subunits.
'As a selective NMDA receptor antagonist, ketamine seems to be binding to a subreceptor that's responsible for the symptoms that patients with these syndromes experience.