NMDA


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NMDA

Abbreviation for N-methyl-d-aspartate; an excitotoxic amino acid used to identify a specific subset of receptors of glutamate (an excitatory amino acid).

NMDA

N-methyl-D-asparate
References in periodicals archive ?
11] Since in this study, only cardiovascular responses are blocked in APV pre-treated group, it is presumable that NMDA receptor blocker interacts with ketamine recognition site of 5-[HT.
On the other hand, there is an impressive body of evidence that, unlike the hypofunction of NMDA receptors in schizophrenia, there appears to be increased activity of NMDA receptors in both unipolar and bipolar depression.
Nonetheless, these syndromes highlight the importance of NMDA receptor signaling for the genesis of symptoms associated with psychotic disorders.
MK-801 is an NMDA receptor antagonist leading to a number of cognitive disorders associated with schizophrenia.
Since dextromethorphan acts on NMDA receptors, the findings suggest that people with fibromyalgia do not have a "radically altered" NMDA system, according to Staud's team.
It has been reported that p receptors activation by opioids also leads to a sustained increase in glutamate synaptic effectiveness at the level of NMDA receptor leading to its activation 3.
This approach was based on the premise that after ingesting the NMDA supplement, muscle mass and strength may be preferentially affected compared to placebo, due to elevations in endogenous testosterone and decreases in cortisol and prolactin.
Hasan said that after a learning phase, the animals' reflex is to close their eye when they hear just the tone, asserting that without NMDA receptors in the primary motor cerebral cortex, the genetically modified mice on the other hand cannot remember the connection between the tone and electrical stimulus, and therefore they keep their eyes open despite the tone.
In this study, we tested the hypothesis that the antinociceptive effects of OMT on neuropathic pain through regulation of NR2B-containing NMDA receptor-ERK/CREB signaling.
The NMDA receptor is widely recognized as the master switch for learning and memory, and a large body of preclinical and clinical research supports targeting this receptor to treat a broad range of neuropsychiatric diseases and cognitive dysfunction.
The most important of these ionotropic receptors are the NMDA (n-methyl-daspartate) and AMPA (a-amino-3-hydroxy5-methylisoxazole-4-propionic acid) receptors.