NKX2-3

NKX2-3

A gene on chromosome 10q24.2 that encodes a putative transcription  factor of unknown function.
References in periodicals archive ?
In addition to the reported disease-specific loci, UC and CD share some susceptibility genes, such as IR23, IL12B, NKX2-3, and MST1.
The transcription factor NKX2-3 regulates the correct localization of lymphocytes and may further contribute to the immune response in intestinal tissue that induces IBD [16].
Because Bmp2/4 is not antagonized by Pinhead, it activates the regulatory genes specifically expressed in the ventral epidermis, including Nkx2-3 (formerly called Nk4), via autocrine signaling.