IL32

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IL32

A gene on chromosome 16p13.3 that encodes interleukin-32, a cytokine which may play a role in innate and adaptive immune responses. It induces other cytokines, including TNFA/TNF-alpha and IL8, and activates the NF-kappa-B and p38 MAPK signal pathways.
References in periodicals archive ?
It is reported that NK4 (natural killer cell transcript-4) stimulates numerous pro-inflammatory cytokines, namely tumor necrosis factor-a as well as IL-8, therefore the name of NK4 was changed as IL-32 [9,10].
2006), and an NK4 gene was shown to be involved in muscle development in the cephalopod Sepia officinalis (Linnaeus, 1758) (Navet et al.
Lo anterior sugiere que la solucion nutritiva NK4 con una relacion N/K 0,45 tuvo un efecto negativo al reducir la produccion de flores en planta de gerbera respecto a las soluciones nutritivas con relacion N/K 1,16; 0,75; y 0,55.
Its NK2 Double is a two-ply, fold-up door that can be made in sizes of up to 28-m wide by 25-m high (92-ft x 82-ft), while its NK4 Warm adds a further two insulation layers to the basic structure to provide additional defenses against external cold.
The HGF/SF-induced phosphorylation of paxillin, matrix adhesion, and invasion of prostate cancer cells were suppressed by NK4, an HGF/SF variant.
Sequence alignments (tBlastn) using homeodomains of proteins belonging to NK2, NK3, NK4, NK5, NK6, NK7, Msx, Hex, and Tlx families were derived from Lottia gigantea, Branchiostoma floridae, and Ciona intestinalis genome contigs available at http://genome.
a biopharmaceutical company developing cancer therapeutics, have formed a collaboration under which Biolex will use its LEX System(TM) for protein expression to create a commercial line for Kringle's NK4 protein.
Work by Professor Wen Jiang, of the Wales College of Medicine and funded by Breast Cancer Campaign, had identified a substance called NK4 - a new version of HGF - which actually inhibits the growth of a tumour.
Scientists in Japan have found that a protein fragment dubbed NK4 can stall the development of pancreatic cancer in mice.
They said NK4 is a protein that blocks the receptors of cancer cells and prevents the cells from replicating.
A substance known only as NK4 holds the key to preventing thousands of women and their families from being devastated by the most common form of female cancer in Wales.
A grant from the Breast Cancer Campaign will enable Dr Weng Jiang and colleague Dr Chris Parr, based at the University of Wales College of Medicine, to carry on their work into proteins NK4 and HGF.