NKX2-2(redirected from NK2 transcription factor related, locus 2)
NKX2-2A gene on chromosome 20p11.22 that encodes a transcription activator required for maintaining NEUROD1 expression in the endocrine pancreas. NKX2-2 may be involved in specifying diencephalic neuromeric boundaries and controlling gene expression during axonal guidance. It associates with chromatin at the NEUROD1 promoter regions.
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