NK1


Also found in: Acronyms.

NK1

Abbreviation for neurokinin-1 antagonist.
References in periodicals archive ?
Serlopitant is a once-daily oral NK1 receptor antagonist under development specifically for treatment of severe chronic pruritus.
CINVANTI is based on the most widely used NK1 receptor antagonist, with almost 9 years of safety and efficacy experience, said Barry D.
A nivel de soluciones nutritivas, como se ha mencionado anteriormente, los cvs que recibieron la solucion NK4 con relacion N/K 0,45 redujeron el numero de flores respecto a las soluciones nutritivas NK1, NK2 y NK3 (p [less than or equal to] 0,01).
For molecular and cellular characterization, synaptic mechanisms underlying the sensitization of spinal cord NK1 expressing neurons are also studied.
Los receptores NK1 parecen tener un papel mas amplio que los receptores 5-HT3 en la genesis del vomito, puesto que los antagonistas de los receptores NK1 son capaces de controlar tanto el vomito agudo como el retardado.
3] receptors and substance P acting on NK1 receptors, activate the CPG and lead to nausea, prodromal symptoms and vomiting.
Mouse CD1-specific NK1 T cells: development, specificity, and function.
Finalmente maduran a celulas NK1 que producen IFN-[gamma] y son totalmente citotoxicas (72).
NK1 almac alt tipi substans P icin ozellikle yuksek tutunma ozelligi gosterir ve onun araciligiyla ensamatuar ve etki meydana gelir.
Pruritus/ Prurigo: Ozellikle hicbir somatik nedenin bulunamadigi kronik pruritus'ta (>6 ay) MSS ve deride strese duyarli karmasik noronal baglantilar ve norobiyolojik mekanizmalar oldugu ileri surulmekte, patogenezde NGF, SP and NK1 gibi NP'ler suclanmaktadir.
Mice that lack the NK1 receptor have been found to consume lower quantities of alcohol compared with control animals, and in a human laboratory model, an antagonist of neurokinin 1, LY686017, was found to reduce spontaneous as well as stress-and alcohol-cue--induced craving for alcohol in alcohol-dependent individuals (George et al.