The test vaccine contains no thimerosal or adjuvant, according to NIAID
supports a number of international research programs on infectious diseases, including HIV/AIDS.
Many expand or build upon existing NIAID
bioterrorism or infectious disease research programs.
In another research study, scientists supported by NIAID
found that an investigational flu vaccine sprayed as a fine mist into children's nostrils is highly effective in preventing both the flu and otitis media, a common flu-related ear infection.
As the regulatory sponsor, NIAID
ensures the trial follows the study protocol and informs the FDA of any significant adverse events or risks.
Following the additional NIAID
award, the company's BCX4430 development contract has been increased in value to USD26.
In Fall 2003, the company was awarded a contract by the NIAID
in the United States to develop and produce an inactivated coronavirus vaccine against Severe Acute Respiratory Syndrome (SARS) for use by the NIH in phase I/II clinical trials.
The research supported by this RFA will contribute to meeting the goals for host defense described in the NIAID
Strategic Plan for Biodefense, which is located at: http://www2.
The AP published selected internal NIAID
emails, memos and reports (see links to these documents below).
Shaden Kamhawi, a medical entomologist also at NIAID
, says the new research "is great, because we really don't know the intricacies of what's going on [in leishmania] transmission.
could have used this funding process to create a clinical trial infrastructure built for such research.
Although investigators have hypothesized that a two-stage TB skin test might be more reliable than a single-stage test in HIV-infected individuals, a recently completed NIAID
study found this not to be the case.