Wherein the NH2-terminal
CUB domain (CUB1) is encoded by exons 2 and 3, whereas the second CUB domain (CUB2) is encoded by exons 4 and 5 and by part of exon 6.
CYANIDIN 3-GLUCOSIDE PROTECTS 3T3-L1 ADIPOCYTES AGAINST H2O2-OR TNF-ALPHA-INDUCED INSULIN RESISTANCE BY INHIBITING C-JUN NH2-TERMINAL
It is well known that the NH2-terminal
regions of LT and CT exhibit the highest degree of homology (91%), while the COOH-terminal region, containing the sole cystine residue in each toxin is less conserved (~52%).
20 peptide inhibits the voltage-gated [Ca.
A glycosylated hemoglobin is formed spontaneously in red blood cells by the combination of the NH2-terminal
amino groups of the hemoglobin beta chain and glucose.
Stress signals activate the c-Jun NH2-terminal
kinase (JNK) and p38 pathways to produce stress response, growth arrest, and apoptosis.
Through the course of thrombin activation, fibrinogen has been shown to release 3 major forms of fibrinopeptide A (FPA) (13): the unmodified form ADSGEGDFLAEGGGVR (FPA), which constitutes ~70%, an NH2-terminal
truncated FPA (des-Ala FPA; ~10%), and a product in which Ser-3 is phosphorylated (P-FPA; ~20%).
05) in the expression of certain enzymes involved in the intra-cellular response to inflammation, including the stress- activated protein kinase c-Jun NH2-terminal
Western blot analysis showed that VK3 induced rapid phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun NH2-terminal
kinase (JNK) 30 minutes after application.