NGU


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NGU

abbr.
nongonococcal urethritis

NGU

abbreviation for nongonococcal urethritis.

NGU

Non-gonococcal urethritis

urethritis

(ur?e-thrit'is) [ urethra + -itis]
Inflammation of the urethra.

anterior urethritis

Inflammation of that portion of the urethra anterior to the anterior layer of the triangular ligament.

gonococcal urethritis

Urethritis caused by Neisseria gonorrhoeae.

nongonococcal urethritis

Abbreviation: NGU
Urethral inflammation caused by organisms other than Neisseria gonorrhoeae. NGU is the most common sexually transmitted disease in men; it accounts for 4 to 6 million physician visits annually. The symptoms usually include painful urination and a urethral discharge. The two organisms most frequently associated with NGU are Chlamydia trachomatis and Ureaplasma urealyticum. Other causes include herpes simplex virus, Trichomonas vaginalis, Haemophilus influenzae, Gardnerella vaginalis, and Clostridium difficile.

Treatment

NGU due to C. trachomatis or U. urealyticum is treated with doxycycline or azithromycin. Appropriate antibiotics are used for other causative organisms.

nonspecific urethritis

Abbreviation: NSU
Nongonococcal urethritis.

posterior urethritis

Inflammation of membranous and prostatic portions of the urethra.

specific urethritis

Urethritis due to a specific organism, usually gonococcus.

nongonococcal urethritis

Abbreviation: NGU
Urethral inflammation caused by organisms other than Neisseria gonorrhoeae. NGU is the most common sexually transmitted disease in men; it accounts for 4 to 6 million physician visits annually. The symptoms usually include painful urination and a urethral discharge. The two organisms most frequently associated with NGU are Chlamydia trachomatis and Ureaplasma urealyticum. Other causes include herpes simplex virus, Trichomonas vaginalis, Haemophilus influenzae, Gardnerella vaginalis, and Clostridium difficile.

Treatment

NGU due to C. trachomatis or U. urealyticum is treated with doxycycline or azithromycin. Appropriate antibiotics are used for other causative organisms.

See also: urethritis
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Although the CDC STD guidelines recommend either doxycycline or azithromycin for the presumptive treatment of NGU, (2) due to the rising recognition of M.
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The explanation for the observed higher failure rate with azithromycin compared with doxycycline in treating chlamydial NGU is probably twofold: homotypic resistance of the organism to a single dose of a bacteriostatic antibiotic, coupled with heterotopic resistance stemming from a persistent subpopulation of cells haying a reduced growth rate within the larger pathogen load, Dr.
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The impact of using azithromycin 1 g as first-line therapy for NGU is illustrated by the markedly contrasting prevalence of macrolide-resistant M.
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genitalium-positive NGU was 28% (15%-45%) in this study and was associated with recurrent urethral symptoms in 8 of 9 cases.
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