NFKB1


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NFKB1

A gene on chromosome 4q24 that encodes a kappa light polypeptide of NF-kappaB (nuclear factor-kappaB), a rapidly acting primary transcription factor which is found in all cell types and involved in cellular responses to stimuli, including cytokines and stress. NF-kappaB plays a key role in regulating the immune response to infection; it is involved in various biological processes including inflammation, immunity, differentiation, cell growth, tumourigenesis and apoptosis.
References in periodicals archive ?
Of the 81 SNPs identified, the rs4648127 SNP, which is located within the NFKB1 gene, was associated with lung cancer in both analyses.
Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence.