SCN9A

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SCN9A

A gene on chromosome 2q24 that encodes an alpha subunit of the voltage-gated sodium channel, which mediates voltage-dependent sodium ion permeability of excitable membranes. The SCN9A protein product plays a major role in nociception signalling.

Molecular pathology
SCN9A mutations are associated with primary erythromelalgia, channelopathy-associated insensitivity to pain and paroxysmal extreme pain disorder.
References in periodicals archive ?
Considering that the freshmen are only a few months into high school, don't drive or even have a permit yet whereas Baty-Barr and Nena are approaching graduation and are already getting excited about the next chapter in their lives, you have a unique make-up of a team.
Caption: Chelan County Commissioner Keith Goehner congratulates Nena Howell while Kevin Overbay and Mike Short join in welcoming Nena.
As in most NENA dialects, the possibility of incorporating a pronominal object within the ergative paradigm of the preterit is confined in Diyana to the 3rd person: sud[??]rre 'he sent him', sudrale 'he sent her', sudrele 'he sent them'.
En "El rastro de tu sangre en la nieve", los personajes de la historia, Nena Daconte y Billy Sanchez de Avila, parten hacia Europa desde Cartagena de Indias para pasar su luna de miel.
NNA - Most countries in the Near East and North Africa (NENA) achieved their international pledge to reduce the share of their population suffering from hunger, but conflicts and protracted crises in Iraq, Sudan, Syria and Yemen, as well as the West Bank and the Gaza Strip, mean that NENA is the only region to have seen its overall prevalence of undernourishment (PoU) increase from the level of a quarter of a century ago.
nance of the park's Victorian pavilion, maintenance of the bowling green and public access to the Friends of the park and local residents' group NENA fear that by the time the 100th birthday arrives in August there will be little to celebrate.
According to FAO, the Nena (Near East and North Africa) region relies on food imports to meet over 50 per cent of its total food requirements and still experiences a food deficit.
Amman, June 17 (Petra) - The Near East-North Africa (NENA) Soil Partnership Conference kicked off in Amman on Tuesday, organized by the Ministry of Agriculture with the support of the Food and Agriculture Organization of the United Nations (FAO).
1984 Nena - 99 Red Balloons UPBEAT cold war protest song 99 Luftballons was released by the German singer Nena.
But Charlie was handed the sash, and holiday prize, after winner Nena France was barred from travelling to the Indian Ocean resort by the top model agency she's signed for.
14 -- Etisalat Lanka Private Limited made donation towards the Presidential Bokk Project 'Nena Guna Thilina' at the Presidential Secretariat.