DLG3(redirected from NEDLG)
DLG3A gene on chromosome Xq13.1 that encodes a member of the membrane-associated guanylate kinase (MAGUK) family thought to play a role in clustering of NMDA receptors at excitatory synapses; it may also downregulate cell proliferation by interacting with the C-terminal region of the adenomatosis polyposis coli tumour suppressor protein. DLG3 is also the retired HUGO symbol for what is now designated MPP3, see there.
DLG3 mutations are associated with X-linked mental retardation.
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