NASCET


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NASCET

Cardiology A clinical trial–North American Symptomatic Carotid Endarterectomy Trial designed to compare the outcomes of surgery plus medical therapy with medical therapy alone in Pts at risk for TIAs and CVAs. See Stroke, Transient ischemic attack.
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Not every person with carotid stenosis or even carotid occlusion will suffer a disabling or terminal stroke, as described in the ACAS and NASCET trials.
Carotid endarterectomy is one of the most common vascular operations since publication of the NASCET and ACAS trials indicating its use as stroke prevention for both asymptomatic and symptomatic carotid stenosis.
NASCET = North American Symptomatic Carotid Endarterectomy Trial
Which of the following is true concerning the NASCET trial?
Sus criterios de inclusion fueron: pacientes que cumplian con los criterios NASCET, estenosis mayores del 60%, pacientes sintomaticos en los ultimos 180 dias antes del procedimiento, y pacientes asintomaticos de alto riesgo).
The NASCET study involved 659 subjects with 70% to 99% carotid stenosis and ipsilateral hemispheric or retinal TIA, or stroke.
The perioperative mortality and major stroke morbidity achieved by NASCET investigators (Table 1) was excellent, and can readily be accepted as a benchmark.
In the NASCET study, absolute risk reduction with surgery for all ipsilateral stroke was 26% among patients with 90% to 99% stenosis, 18% among patients with 80% to 89% stenosis, and 12% among patients with 70% to 79% stenosis.
The NASCET study population comprised 28% retinal TIA or stroke patients, 38% hemispheric TIA patients, and 34% hemispheric stroke patients.