NADPH


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NADPH

Abbreviation for nicotinamide adenine dinucleotide phosphate (reduced form).
Farlex Partner Medical Dictionary © Farlex 2012

NADPH

(ĕn′ā-dē′pē-āch′)
n.
The reduced form of NADP.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
References in periodicals archive ?
NADPH oxidase was measured based on its capacity to reduce ferricytochrome c in ferrocytochrome at pH of 7.8 (22).
Leptin induces oxidative stress through activation of NADPH oxidase in renal tubular cells: Antioxidant effect of L-carnitine.
The NADP+ and NADPH levels were quantified via enzymatic cycling, using the phenazine methosulfate (PMS)-catalyzed reduction thiazolyl blue (MTT) method in the presence of glucose 6-phosphate (G6P) for NAD[P.sup.+], and glucose 6-phosphate dehydrogenase (G6PDH) for NADPH.
After hypoxia/reoxygenation (H/R) treatment for 24 h, (A) intracellular ROS production was analyzed by H2DCF-DA in H9c2 cells; (B) mitochondria ROS production was detected by MitoSOX Red assay; (C) the activity of NADPH oxidase was measured by chemiluminescence assay; (D) the protein level of NOX2 was examined by western blot.
Km and Vmax values for NADPH were 85 [mirco]mol and 4.8 [mirco]mol/min/mg, respectively (Figure 5).
Moreover, OS was prominent in the juvenile female mouse model of NAFLD/NASH and the mechanism might be related to the activation of the liver NADPH oxidase.
Inhibition of diaphorase activity of PfFNR was measured in the reaction of Scheme 1 as described above, by the additions of each alkaloid at 100 ppm, NADPH at 100 uM, and 5 nM FNR.
Caption: FIGURE 1: Extract ion (m/z 956 [right arrow] 817) chromatograms obtained from LC-LTQ MS analysis of microsomal incubations containing LIM, GSH, NAL, and NADPH in the absence microsomes (a), or in presence of HLMs (b) or MLMs (c).
Accordingly, although high glucose levels did not change EMPs' morphology (i.e., size and antigen composition), the hyperglycemia increases the functionality of EMPs in activating NADPH oxidase/[p38.sup.phox]-mediated signaling when compared to EMPs formed in a normoglycemic environment [53].