methionine synthase
(redirected from N5-methyltetrahydrofolate:homocysteine methyltransferase)me·thi·o·nine syn·thase
tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase; an enzyme that catalyzes the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.
Synonym(s): tetrahydrofolate methyltransferase
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methionine synthase
(1) 5-Methyltetrahydrofolate-homocysteine S-methyltransferase, EC 2.1.1.13.(2) O-Acetylhomoserine (thiol)-lyase, EC 4.2.99.10.
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