N-terminal

N-terminal

 [ter´min-al]
the amino (NH2) end of a polypeptide chain, conventionally written to the left.
References in periodicals archive ?
Juraschek, M.D., Ph.D., from Harvard Medical School in Boston, and colleagues evaluated high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements from participants in the Atherosclerosis Risk in Communities Study without known coronary heart disease, heart failure, or stroke.
Her expertise will be instrumental in advancing the clinical development of ESSA's novel N-terminal domain inhibitor of the androgen receptor in men with prostate cancer.'
These instruments are designed to provide higher sensitivity and more reliable analysis of N-terminal amino acid sequences through automated Edman degradation.
The N-terminal amino acid sequences of globin chains were obtained by the process of Edman degradation in an automated protein sequencer using an online Phenylthiohydantoin (PTH) analyzer.
Objective: To detect the serum levels of D-dimer and N-terminal pro B-type natriuretic peptide (NT-pro BNP) in patients with Acute Ischemic Stroke (AIS), and to explore the risk factors of AIS.
Contract awarded for Supply of bombesin (1-14) analogue, n- terminal dota,aa sequence pro-gln-arg-tyr-gly-asn-gln-trp-ala-val-gly-his-leu-met,residues 14, c-terminal nh2 , peptidename: bombesin (1-14) analogue, n-terminal: dota, c-terminal: nh2, residues: 14, purity: greater than 95% as per annexure a
Furthermore, MoBiTec offers vectors encoding C- or N-terminal His-tags for easy purification.
In their study of 1079 AMI patients, these authors analyzed the associations of TMAO with all-cause mortality or reinfarction in comparison with other biomarkers [including N-terminal pro-B-type natriuretic peptides (NT-proBNP)].
The basic principle of this test involves the N-terminal region of human albumin and its inherent affinity for the cobalt metal ion (the so-called albumin cobalt binding, or ACB assay), the premise being that during myocardial ischemia, the albumin cobalt binding affinity is reduced due to an N-terminal modification of albumin [1, 2].
[9] demonstrated that N-terminal but not C-terminal antibody to PAX8 by IHC was present in reactive and neoplastic B lymphoid cells yet PAX8 mRNA levels were not detectable in any B-cell lymphoma cell lines studied by qRT-PCR methods.
In order to obtain soluble and stable glycosylated proteins we chose to express the wild-type hIFN[gamma] and its mutant K88Q as secretory N-terminal [His.sub.6]-FLAG fusion proteins in baculovirus-infected insect (Trichoplusia ni) High Five[R] cells.
After the binding to one of these receptors PA undergoes a proteolytical processing by the furine class membrane protease which removes PA N-terminal 20 kDa domain (domain I, PA20).