Compont[R] medical adhesive is one of synthetic cyanoacrylates approved by China Food and Drug Administration, containing n-butyl-cyanoacrylate
. It rapidly creates a thin elastic film of high tensile strength in the presence of anions in the blood, with a reticular structure that ensures firm adherence to tissues.
A total of 652 patients who underwent N-butyl-cyanoacrylate
(NBCA) injection as secondary prophylaxis for gastric variceal hemorrhage were identified.
Compared to endoscopic injection sclerotherapy (EIS) or endoscopic variceal ligation (EVL), endoscopic variceal obturation with a tissue adhesive such as N-butyl-cyanoacrylate
, or isobutyl-2-cyanoacrylate is more effective for acute fundic gastric variceal bleeding.
Gastric varices were treated with N-butyl-cyanoacrylate
using the sandwich method (lipiodol or 20% glucose or lauromacrogol-cyanoacrylate-lipiodol or 20% glucose or lauromacrogol).
These authors used n-butyl-cyanoacrylate in the lacrimal canaliculi of rabbits and observed local diffuse inflammatory response on days 7 and 14 after occlusion.
These authors reported that histological evaluation showed elevated inflammatory response 4 and 6 days after n-butyl-cyanoacrylate application.
Trans-arterial embolisation therapy of dural carotid-cavernous fistulae using low concentration n-butyl-cyanoacrylate
. Acta Neurochir (Wien) 2008; 150: 1149-56.