Myositis, inclusion body | definition of Myositis, inclusion body by Medical dictionary
inclusion body myositis (redirected from Myositis, inclusion body)
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inclusion body myositis
a slowly progressive inflammatory myopathy with a male predominance and preferential weakness onset in the quadriceps muscles, finger flexors, or pharyngeal muscles. Inflammatory infiltrate can be observed, with a predominance of CD8+ T cells.
inclusion body myositis A type of idiopathic myositis that is not autoimmune and does not respond to immunosuppressive therapy, a clinical diagnosis of exclusion, confirmed by typical histologic features Clinical Slowly progressive disease of middle-aged ♂, beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing of nerve conduction and ↑ wave amplitude