MERRF syndrome

(redirected from Myoclonic Epilepsy with Ragged Red Fibers)

MERRF syndrome

 
myoclonus with epilepsy and ragged red fibers; a familial type of mitochondrial encephalopathy, of maternal (mitochondrial) inheritance.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
We read with interest the case report by Ban et al .[1] about a 17-year-old male with myoclonic epilepsy with ragged red fibers (MERRF) syndrome being attributed to the mitochondrial tRNA glutamic acid( tRNA [Glu] )variant mitochondrial 14709T>C.
Soon after this, point mutations in the mitochondrial tRNA genes were found in patients with complex disorders such as myoclonic epilepsy with ragged red fibers and mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes [6, 7].
Background: Myoclonic epilepsy with ragged red fibers (MERRF) syndrome is characterized by myoclonus, generalized epilepsy, cerebellar ataxia, and ragged red fibers (RRFs) in the muscle.