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a hemoprotein having peroxidase activity, occurring in the primary granules of promyelocytes, myelocytes, and neutrophils, and that exhibits bactericidal, fungicidal, and viricidal properties.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A peroxidase occurring in phagocytic cells that can oxidize halogen ions (for example, I-) with hydrogen peroxide to the free halogen, also producing two water molecules; an autosomal recessive deficiency of myeloperoxidase leads to impaired bacterial killing; formerly called verdoperoxidase because it is green. Compare: verdoperoxidase.
Farlex Partner Medical Dictionary © Farlex 2012
MPOA gene on chromosome 17q23.1 that encodes myeloperoxidase during myeloid differentiation. MPO is the major component of neutrophil azurophilic granules and produces hypohalous acids (e.g., hypochlorous acid) and other toxic intermediates central to the microbicidal activity of netrophils.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.