myelinopathy

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my·e·lin·op·a·thy

(mī'ĕ-lin-op'ă-thē),

A disorder affecting the myelin of peripheral nerve fibers, in contrast to one affecting axons (axonopathy).

Farlex Partner Medical Dictionary © Farlex 2012

myelinopathy

(mi?e-li-nop'a-the)

Degeneration of the myelin sheaths of neurons, esp. in the central nervous system.

See: multiple sclerosis

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References in periodicals archive ?

Canavan disease (CD) is a leukodystrophy characterized by the degeneration of white matter that is replaced by fluid, thereby causing vacuolating myelinopathy (1, 2).

Canavan Disease: First Normocephalic Case from North Cyprus

(1-3) The electrophysiological examination including both nerve conduction and electromyography studies should identify peripheral nerve dysfunction if present, along with the specific location in the nerve pathway, involvement of sensory and/or motor axons, and the presence of myelinopathy and/or axonopathy neuropathic process.

GEHS Neurophysiological Classification System for Patients with Neuropathy of the Ulnar Nerve at the Elbow

Haginoya et al., "Schinzel-Giedion syndrome: A further cause of early myoclonic encephalopathy and vacuolating myelinopathy," Brain & Development, vol.

Schinzel-Giedion Syndrome with Congenital Megacalycosis in a Turkish Patient: Report of SETBP1 Mutation and Literature Review of the Clinical Features

(1) The coalescence of vacuoles formed between myelin lamellae in the oligodendroglia results in a pattern termed "vacuolating myelinopathy" when seen under electron microscopy.

Heroin-associated spongiform leukoencephalopathy

Avian vacuolar myelinopathy (AVM) is a neurologic disease causing recurrent mortality of bald eagles (Haliaeetus leucocephalus) and American coots (Futica americana) at reservoirs and small impoundments in the southern USA.

J Wildl Dis.: Alternative food-chain transfer of the toxin linked to avian vacuolar myelinopathy and implications for the endangered Florida snail kite (Rostrhamus sociabilis)

Disease Pathology Inheritance Genes/chromosomal name (a) mode loci associated with disease, n CMT1 Abnormal myelin AD (b) 9 CMT2 Axonopathy AD 19 CMT4 Either myelinopathy AR 10 or axonopathy CMTX Axonopathy with XLD 2 secondary myelin changes Disease Proportion name (a) of all CMT, % CMT1 40-50 CMT2 10-15 CMT4 Rare CMTX 10-15 (a) Intermediate dominant (dominant inheritance with NCV between demylinating and axonopathic) and other rare forms are not included.

Increased serum creatine kinase

(4,12) Triggs and Cros wrote a letter to the editor of Neurology by citing their paper and ours, suggesting that the entire findings in GBS patients were produced by only a primary myelinopathy. (4,35-38) We responded to their comments by suggesting that an animal model of GBS inoculated with C.

Guillain-Barre syndrome and anti-ganglioside antibodies: a clinician-scientist's journey

Additionally, hydrilla has been implicated in the spread of an emerging avian disease known as avian vacuolar myelinopathy that affects herbivorous waterbirds and their predators (11), (12), (13).

Effects of hydrilla control on wintering waterfowl at lake Seminole, Georgia

But there is the same genetically caused myelin sheath damage of peripheral nerves (myelinopathy) in pathogenesis in majority of them.

Method of computer esthesiometry on distal parts of the lower extremities in diagnostics of Charcot-Marie-Tooth disease

Inherited spinal myelinopathy in Murray Gray cattle.

Mieloencefalopatia degenerativa progressiva hereditaria (Sindrome da Oscilacao) em bezerros Gir

Researchers at the University of Georgia are working to determine the cause of Avian Vacuolar Myelinopathy which has killed eagles and other birds in four states, which is currently unknown.