mycobacterium simiae

mycobacterium simiae

A mycobacterium, first isolated from rhesus macaques in 1965. It is a slow-growing photochromogen, appearing rust-coloured after exposure to light, and is the only nontuberculous mycobacterium that, like M tuberculosis, is niacin positive. Most isolates of M simiae have been reported from the southwestern US, Cuba and Israel. Its environmental niche is believed to be aquatic.

Clinical finding
M simiae infection most commonly occurs in HIV-positive patients with pulmonary disease as well as lymphadenopathy, skin lesions and genitourinary tract involvemen. M simiae may cause infection (e.g., regional lymphadenopathy) in immunocompetent hosts.

Management
Isoniazid, rifampin, ethambutol.

My·co·bac·te·ri·um sim·i·ae

(mī'kō-bak-tēr'ē-ŭm sim'ē-ē)
A slow-growing, photochromogenic, acid-fast bacillus; rarely associated with pulmonary disease in humans.
References in periodicals archive ?
Spindle cell pseudotumor of the brain associated with Mycobacterium haemophilum and Mycobacterium simiae mixed infection in a patient with AIDS: the first case report.
Suankratay, "Spindle cell pseudotumor of the brain associated with Mycobacterium haemophilum and Mycobacterium simiae mixed infection in a patient with AIDS: the first case report," International Journal of Infectious Diseases, vol.
Graybill, "Disseminated Mycobacterium simiae infection in patients with AIDS," Journal of Infection, vol.
Kanj, "Fatal disseminated Mycobacterium simiae infection in a non-HIV patient," International Journal of Infectious Diseases, vol.
SGM comprise some common species, such as the Mycobacterium avium complex (Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium chimaera), Mycobacterium kansasii, Mycobacterium haemophilum, Mycobacterium marinum, and Mycobacterium ulcerans, in addition to some less common pathogens, such as Mycobacterium scrofulaceum, Mycobacterium simiae, Mycobacterium malmoense and Mycobacterium xenopi.
Rastogi, "A molecular epidemiological study of Mycobacterium simiae isolated from AIDS patients in Guadeloupe," Journal of Clinical Microbiology, vol.
(1,3,4) Other species that have been documented in birds include Mycobacterium tuberculosis, Mycobacterium fortuitum, Mycobacterium gordonae, Mycobacterium nonchromogenicum, Mycobacterium simiae, and Mycobacterium peregrinum.
Characterization of mycobacterial isolates phylogenetically related to, but different from Mycobacterium simiae. J Clin Microbiol.
Among 68 patient episodes of mycobacteremia identified by Myco/F Lytic culture during a 10-year period from 1997 through 2006, there were 59 patients with Mycobacterium avium complex; 6 with Mycobacterium tuberculosis complex; and 3 with Mycobacterium abscessus, Mycobacterium simiae, and coinfection with M avium complex and M kansasii, respectively.
Graybill, "Clinical isolates of Mycobacterium simiae in San Antonio, Texas.
Mycobacterium simiae outbreak associated with a hospital water supply.

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