Mycobacterium avium complex
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Mycobacterium avium complexA group of genetically related mycobacteria including M avium, M intracellulare and M avium subspecies paratuberculosis.
Mycobacterium avium complexAbbreviation: MAC, MAI
MAC infection in AIDS patients can cause fatigue, fever, weight loss, cachexia, pancytopenia, and death.
Multiple antimicrobial agents, given at the same time and for long courses, are required to treat MAC. Combination therapy may include a macrolide with drugs such as rifabutin, ethambutol, ciprofloxacin, amikacin, and/or clofazimine.